Neuregulin 4 antibody

Catalog No. ABIN7260591

Product Details anti-Neuregulin 4 Antibody

Target: Neuregulin 4 (NRG4)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuregulin 4 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human NRG4 (NP_612640.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Neuregulin 4

Target: Neuregulin 4 (NRG4)

Alternative Name: NRG4 (NRG4 Products)

Synonyms: HRG4 antibody, AI552600 antibody, neuregulin 4 antibody, NRG4 antibody, Nrg4 antibody, LOC100347220 antibody

Background: Neuregulin 4also known asNRG4is a member of theneuregulinproteinfamily which in humans is encoded by theNRG4gene. Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors.

Gene ID: 145957

UniProt: Q8WWG1

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway