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Dynamitin antibody

DCTN2 Reactivity: Human, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7260303
  • Target See all Dynamitin (DCTN2) Antibodies
    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
    Reactivity
    • 41
    • 35
    • 16
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 49
    • 5
    • 3
    Rabbit
    Clonality
    • 54
    • 3
    Polyclonal
    Conjugate
    • 32
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Dynamitin antibody is un-conjugated
    Application
    • 45
    • 17
    • 13
    • 13
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human DCTN2 (NP_006391.1).
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
    Alternative Name
    DCTN2 (DCTN2 Products)
    Synonyms
    DCTN2 antibody, dctn2 antibody, dctn50 antibody, dynamitin antibody, rbp50 antibody, CG8269 antibody, DMN antibody, Dmel\\CG8269 antibody, P50 antibody, dDyn antibody, dmn antibody, dyna antibody, l(2)k16109 antibody, l(2)k16218 antibody, p50 antibody, p50/Dmn antibody, p50/dynamitin antibody, 2310042E05Rik antibody, C130077D06Rik antibody, C87049 antibody, DCTN-50 antibody, GMP23-48K antibody, RBP50 antibody, DCTN50 antibody, DYNAMITIN antibody, zgc:63867 antibody, dynactin subunit 2 antibody, dynactin subunit 2 S homeolog antibody, Dynactin 2, p50 subunit antibody, dynactin 2 antibody, dynactin 2 (p50) antibody, dynactin subunit 2 L homeolog antibody, DCTN2 antibody, dctn2.S antibody, DCTN2-p50 antibody, dctn2 antibody, Dctn2 antibody, dctn2.L antibody
    Background
    This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: 44 kDa

    Calculated_MW: 44 kDa

    Gene ID
    10540
    UniProt
    Q13561
    Pathways
    M Phase, Ribonucleoprotein Complex Subunit Organization
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