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IKK alpha antibody
CHUK
Reactivity: Human, Mouse, Rat
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IKK alpha Antibody
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Target
See all IKK alpha (CHUK) Antibodies
IKK alpha (CHUK)
(conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
Reactivity
All reactivities for IKK alpha antibodies
Human, Mouse, Rat
Host
All hosts for IKK alpha antibodies
Rabbit
Clonality
All clonalities for IKK alpha antibodies
Polyclonal
Conjugate
All conjugates for IKK alpha antibodies
This IKK alpha antibody is un-conjugated
Application
All applications for IKK alpha antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
A synthetic peptide of human IKK alpha (NP_001269.3).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200 IF 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for IKK alpha
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Target
IKK alpha (CHUK)
(conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
Alternative Name
IKK alpha (CHUK Products )
Synonyms
ikk antibody, ikk1 antibody, ikka antibody, ikkalpha antibody, CHUK antibody, IKBKA antibody, IKK-alpha antibody, IKK1 antibody, IKKA antibody, NFKBIKA antibody, TCF16 antibody, AI256658 antibody, Chuk1 antibody, Fbx24 antibody, Fbxo24 antibody, Ikka antibody, zgc:56539 antibody, conserved helix-loop-helix ubiquitous kinase S homeolog antibody, conserved helix-loop-helix ubiquitous kinase antibody, chuk.S antibody, CHUK antibody, Chuk antibody, chuk antibody
Background
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Gene ID
1147
UniProt
O15111
Pathways
PI3K-Akt Signaling , NF-kappaB Signaling , RTK Signaling , TCR Signaling , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , Ubiquitin Proteasome Pathway , S100 Proteins
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