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TAPBP antibody

TAPBP Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7260003
  • Target See all TAPBP Antibodies
    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
    Reactivity
    • 36
    • 8
    • 6
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 36
    Rabbit
    Clonality
    • 36
    Polyclonal
    Conjugate
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TAPBP antibody is un-conjugated
    Application
    • 29
    • 14
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human TAPBP (NP_757345.2).
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
    Alternative Name
    TAPBP (TAPBP Products)
    Synonyms
    SI:dZ179B20.1 antibody, SI:dZ179B20.3 antibody, SI:dZ179B20.7 antibody, mhc1uda antibody, mhc1ufa antibody, tpsn antibody, zgc:109814 antibody, tapbp antibody, TAPBP antibody, D17Wsu91e antibody, TPN antibody, NGS17 antibody, TAPA antibody, TPSN antibody, TAP binding protein (tapasin), tandem duplicate 1 antibody, TAP binding protein antibody, tapbp.1 antibody, tapbp antibody, TAPBP antibody, Tapbp antibody
    Background
    This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
    Molecular Weight

    Observed_MW: 48 kDa

    Calculated_MW: 38 kDa/43 kDa/47 kDa/53 kDa

    Gene ID
    6892
    UniProt
    O15533
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