PNPO antibody

Catalog No. ABIN7259861

Product Details anti-PNPO Antibody

Target: PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNPO antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human PNPO.

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PNPO

Target: PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))

Alternative Name: PNPO (PNPO Products)

Synonyms: im:7138360 antibody, ECK1634 antibody, JW1630 antibody, PDXPO antibody, AI415282 antibody, pyridoxamine 5'-phosphate oxidase antibody, pyridoxine 5'-phosphate oxidase antibody, Pyridoxamine 5'-phosphate oxidase antibody, pnpo antibody, pdxH antibody, Mrub_2888 antibody, Arnit_1624 antibody, Ndas_4168 antibody, Mesil_2817 antibody, Isop_0296 antibody, Despr_1960 antibody, Pedsa_1348 antibody, Mesop_5639 antibody, PNPO antibody, Pnpo antibody

Background: The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.

Gene ID: 55163

UniProt: Q9NVS9