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DDB2 antibody

DDB2 Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7009799
  • Target See all DDB2 Antibodies
    DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
    Reactivity
    • 37
    • 16
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 36
    • 3
    Rabbit
    Clonality
    • 27
    • 12
    Polyclonal
    Conjugate
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This DDB2 antibody is un-conjugated
    Application
    • 21
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human DDB2 (NP_000098.1).
    Isotype
    IgG
    Top Product
    Discover our top product DDB2 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
    Alternative Name
    DDB2 (DDB2 Products)
    Synonyms
    2610043A19Rik antibody, si:dkey-45f10.3 antibody, DDBB antibody, UV-DDB2 antibody, damage specific DNA binding protein 2 antibody, damage-specific DNA binding protein 2 antibody, DDB2 antibody, ddb2 antibody, Ddb2 antibody
    Background
    This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: 48 kDa

    Calculated_MW: 17 kDa/26 kDa/40 kDa/47 kDa

    Gene ID
    1643
    UniProt
    Q92466
    Pathways
    DNA Damage Repair
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