Surfactant Protein C antibody

Catalog No. ABIN7259843

Product Details anti-Surfactant Protein C Antibody

Target: Surfactant Protein C (SFTPC)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Surfactant Protein C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SFTPC (NP_001165881.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Surfactant Protein C

Target: Surfactant Protein C (SFTPC)

Alternative Name: SFTPC (SFTPC Products)

Synonyms: SFTPC antibody, SPC antibody, SP-C antibody, psp-c antibody, sftp2 antibody, xSP-C antibody, Bricd6 antibody, SP5 antibody, Sftp-2 antibody, Sftp2 antibody, pro-SpC antibody, BRICD6 antibody, PSP-C antibody, SFTP2 antibody, SMDP2 antibody, surfactant protein C antibody, surfactant, pulmonary-associated protein C S homeolog antibody, surfactant, pulmonary-associated protein C antibody, surfactant associated protein C antibody, SFTPC antibody, sftpc.S antibody, sftpc antibody, Sftpc antibody

Background: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Molecular Weight:

Observed_MW: 21 kDa

Calculated_MW: 20 kDa/21 kDa

Gene ID: 6440

UniProt: P11686