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IL-10RA antibody

IL10RA Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7259833
  • Target See all IL-10RA (IL10RA) Antibodies
    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
    Reactivity
    • 83
    • 37
    • 18
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 75
    • 13
    • 10
    • 2
    Rabbit
    Clonality
    • 76
    • 22
    • 1
    Polyclonal
    Conjugate
    • 53
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-10RA antibody is un-conjugated
    Application
    • 66
    • 32
    • 18
    • 13
    • 12
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human IL10RA (NP_001549.2).
    Isotype
    IgG
    Top Product
    Discover our top product IL10RA Primary Antibody
  • Application Notes
    IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
    Alternative Name
    IL10RA (IL10RA Products)
    Synonyms
    IL10R1 antibody, IL10RA antibody, CD210 antibody, CD210a antibody, CDW210A antibody, HIL-10R antibody, IL-10R1 antibody, IL10R antibody, AW553859 antibody, CDw210 antibody, CDw210a antibody, Il10r antibody, mIL-10R antibody, interleukin 10 receptor subunit alpha antibody, interleukin 10 receptor, alpha antibody, IL10RA antibody, Il10ra antibody
    Background
    The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
    Gene ID
    3587
    UniProt
    Q13651
    Pathways
    Growth Factor Binding
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