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IL-10RA antibody
IL10RA
Reactivity: Human, Mouse, Rat
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IL-10RA Antibody
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Target
See all IL-10RA (IL10RA) Antibodies
IL-10RA (IL10RA)
(Interleukin 10 Receptor, alpha (IL10RA))
Reactivity
All reactivities for IL-10RA antibodies
Human, Mouse, Rat
Host
All hosts for IL-10RA antibodies
Rabbit
Clonality
All clonalities for IL-10RA antibodies
Polyclonal
Conjugate
All conjugates for IL-10RA antibodies
This IL-10RA antibody is un-conjugated
Application
All applications for IL-10RA antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human IL10RA (NP_001549.2).
Isotype
IgG
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Discover our top product IL10RA Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200 IF 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for IL-10RA
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Target
IL-10RA (IL10RA)
(Interleukin 10 Receptor, alpha (IL10RA))
Alternative Name
IL10RA (IL10RA Products )
Synonyms
IL10R1 antibody, IL10RA antibody, CD210 antibody, CD210a antibody, CDW210A antibody, HIL-10R antibody, IL-10R1 antibody, IL10R antibody, AW553859 antibody, CDw210 antibody, CDw210a antibody, Il10r antibody, mIL-10R antibody, interleukin 10 receptor subunit alpha antibody, interleukin 10 receptor, alpha antibody, IL10RA antibody, Il10ra antibody
Background
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Gene ID
3587
UniProt
Q13651
Pathways
Growth Factor Binding
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