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FKBP1A antibody

FKBP1A Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7259707
  • Target See all FKBP1A Antibodies
    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
    Reactivity
    • 57
    • 27
    • 20
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 56
    • 8
    Rabbit
    Clonality
    • 48
    • 16
    Polyclonal
    Conjugate
    • 28
    • 9
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This FKBP1A antibody is un-conjugated
    Application
    • 35
    • 21
    • 18
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human FKBP1A (NP_463460.1).
    Isotype
    IgG
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    Discover our top product FKBP1A Primary Antibody
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
    Alternative Name
    FKBP1A (FKBP1A Products)
    Background
    The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.
    Gene ID
    2280
    UniProt
    P62942
    Pathways
    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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