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GLI2 antibody

GLI2 Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7259424
  • Target See all GLI2 Antibodies
    GLI2 (GLI Family Zinc Finger 2 (GLI2))
    Reactivity
    • 40
    • 11
    • 3
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 39
    • 2
    • 1
    Rabbit
    Clonality
    • 40
    • 2
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    This GLI2 antibody is un-conjugated
    Application
    • 16
    • 10
    • 9
    • 4
    • 4
    • 3
    • 1
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of mouse GLI2.
    Isotype
    IgG
    Top Product
    Discover our top product GLI2 Primary Antibody
  • Application Notes
    IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GLI2 (GLI Family Zinc Finger 2 (GLI2))
    Alternative Name
    GLI2 (GLI2 Products)
    Synonyms
    HPE9 antibody, THP1 antibody, THP2 antibody, GLI2/GLI4 antibody, GLI3 antibody, AW546128 antibody, GLI family zinc finger 2 antibody, GLI-Kruppel family member GLI2 antibody, GLI2 antibody, Gli2 antibody
    Background
    This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.
    Gene ID
    14633
    UniProt
    P10070
    Pathways
    Hedgehog Signaling, Dopaminergic Neurogenesis
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