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CMKLR1 antibody

CMKLR1 Reactivity: Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7259076
  • Target See all CMKLR1 Antibodies
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    Reactivity
    • 68
    • 40
    • 23
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 68
    • 3
    • 2
    Rabbit
    Clonality
    • 67
    • 5
    • 1
    Polyclonal
    Conjugate
    • 29
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CMKLR1 antibody is un-conjugated
    Application
    • 60
    • 28
    • 26
    • 26
    • 19
    • 12
    • 8
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide of human CMKLR1 (NP_001135815.1).
    Isotype
    IgG
    Top Product
    Discover our top product CMKLR1 Primary Antibody
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    Alternative Name
    CMKLR1 (CMKLR1 Products)
    Synonyms
    CHEMERINR antibody, ChemR23 antibody, DEZ antibody, RVER1 antibody, Gpcr27 antibody, mcmklr1 antibody, si:ch211-240b21.3 antibody, CMLKR1 antibody, Cmklr-1 antibody, GPCR antibody, chemerin chemokine-like receptor 1 antibody, chemokine-like receptor 1 antibody, CMKLR1 antibody, Cmklr1 antibody, cmklr1 antibody
    Background
    Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
    Molecular Weight

    Observed_MW: 55 kDa

    Calculated_MW: 42 kDa

    Gene ID
    1240
    UniProt
    Q99788
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