MAP3K3 antibody
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- Target See all MAP3K3 Antibodies
- MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAP3K3 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human MAP3K3 (NP_976226.1).
- Isotype
- IgG
- Top Product
- Discover our top product MAP3K3 Primary Antibody
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anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 1-220) antibody
MAP3K3 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 11-25), (N-Term) antibodyMAP3K3 Reactivity: Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (N-Term) antibodyMAP3K3 Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 1-90) antibodyMAP3K3 Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (Center) antibodyMAP3K3 Reactivity: Human, Mouse, Rat WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (Internal Region) antibodyMAP3K3 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (N-Term) antibodyMAP3K3 Reactivity: Human, Mouse, Rat, Rabbit, Dog, Monkey, Drosophila melanogaster, Guinea Pig, Hamster, Pig, Sheep, Xenopus laevis WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (Internal Region) antibodyMAP3K3 Reactivity: Human, Mouse WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) antibodyMAP3K3 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 1-90) antibodyMAP3K3 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- IHC 1:100-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
- Alternative Name
- MAP3K3 (MAP3K3 Products)
- Synonyms
- MAPKKK3 antibody, MEKK3 antibody, AW548911 antibody, Mekk3 antibody, mKIAA4031 antibody, mitogen activated protein kinase kinase kinase 3 antibody, mitogen-activated protein kinase kinase kinase 3 antibody, Map3k3 antibody, MAP3K3 antibody, map3k3 antibody
- Background
- This gene product is a 626-amino acid polypeptide that is 96.5 % identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively, it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Gene ID
- 4215
- UniProt
- Q99759
- Pathways
- MAPK Signaling
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