EIF5B antibody

Catalog No. ABIN7258398

Product Details anti-EIF5B Antibody

Target: EIF5B (Eukaryotic Translation Initiation Factor 5B (EIF5B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF5B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human EIF5B (NP_056988.3).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EIF5B

Target: EIF5B (Eukaryotic Translation Initiation Factor 5B (EIF5B))

Alternative Name: EIF5B (EIF5B Products)

Synonyms: CIF2 antibody, EIF5B antibody, MGC134193 antibody, im:6912504 antibody, si:ch211-254d18.3 antibody, AO090003000953 antibody, DDBDRAFT_0206214 antibody, DDBDRAFT_0234259 antibody, DDB_0206214 antibody, DDB_0234259 antibody, IF2 antibody, A030003E17Rik antibody, BC018347 antibody, eukaryotic translation initiation factor 5B antibody, translation initiation factor IF-2 antibody, EIF5B antibody, eif5b antibody, EDI_190850 antibody, AOR_1_1690154 antibody, CMU_007690 antibody, POSPLDRAFT_134975 antibody, POSPLDRAFT_134953 antibody, eIF5b antibody, MCYG_03474 antibody, PITG_20386 antibody, eif5B antibody, MGYG_03082 antibody, PGTG_13938 antibody, Eif5b antibody

Background: Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.

Molecular Weight:

Observed_MW: 179 kDa

Calculated_MW: 138 kDa

Gene ID: 9669

UniProt: O60841