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CD11c antibody
ITGAX
Reactivity: Human, Mouse, Rat
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CD11c Antibody
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Target
See all CD11c (ITGAX) Antibodies
CD11c (ITGAX)
(Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
Reactivity
All reactivities for CD11c antibodies
Human, Mouse, Rat
Host
All hosts for CD11c antibodies
Rabbit
Clonality
All clonalities for CD11c antibodies
Polyclonal
Conjugate
All conjugates for CD11c antibodies
This CD11c antibody is un-conjugated
Application
All applications for CD11c antibodies
Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human ITGAX (NP_000878.2).
Isotype
IgG
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Discover our top product ITGAX Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for CD11c
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Target
CD11c (ITGAX)
(Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
Alternative Name
ITGAX (ITGAX Products )
Synonyms
CD11C antibody, SLEB6 antibody, RGD1561123 antibody, AI449405 antibody, Cd11c antibody, Cr4 antibody, N418 antibody, integrin subunit alpha X antibody, integrin alpha X antibody, ITGAX antibody, Itgax antibody
Background
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
3687
UniProt
P20702
Pathways
Complement System , Activated T Cell Proliferation , Integrin Complex
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