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YTHDC2 antibody

YTHDC2 Reactivity: Human, Mouse IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7258258
  • Target See all YTHDC2 products
    YTHDC2 (YTH Domain Containing 2 (YTHDC2))
    Reactivity
    • 6
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 6
    Rabbit
    Clonality
    • 5
    • 1
    Polyclonal
    Conjugate
    • 6
    This YTHDC2 antibody is un-conjugated
    Application
    • 6
    • 3
    • 1
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human YTHDC2 (NP_073739.3).
    Isotype
    IgG
  • Application Notes
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    YTHDC2 (YTH Domain Containing 2 (YTHDC2))
    Alternative Name
    YTHDC2 (YTHDC2 Products)
    Synonyms
    3010002F02Rik antibody, BC037178 antibody, CAHL antibody, YTH domain containing 2 antibody, Ythdc2 antibody, YTHDC2 antibody
    Background
    This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
    Gene ID
    64848
    UniProt
    Q9H6S0
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