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ABCB11 antibody

ABCB11 Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7258050
  • Target See all ABCB11 Antibodies
    ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
    Reactivity
    Human, Mouse, Rat
    Host
    • 21
    • 3
    Rabbit
    Clonality
    • 21
    • 3
    Polyclonal
    Conjugate
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCB11 antibody is un-conjugated
    Application
    • 14
    • 8
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide of human ABCB11 (NP_003733.2).
    Isotype
    IgG
    Top Product
    Discover our top product ABCB11 Primary Antibody
  • Application Notes
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
    Alternative Name
    ABCB11 (ABCB11 Products)
    Synonyms
    ABCB11 antibody, Bsep antibody, ABC16 antibody, BRIC2 antibody, BSEP antibody, PFIC-2 antibody, PFIC2 antibody, PGY4 antibody, SPGP antibody, Lith1 antibody, BSEP/SPGP antibody, Spgp antibody, ATP binding cassette subfamily B member 11 antibody, bile salt export pump antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 11 antibody, ABCB11 antibody, LOC100489744 antibody, LOC100565276 antibody, EDI_111220 antibody, EDI_272930 antibody, abcb11 antibody, Abcb11 antibody
    Background
    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
    Gene ID
    8647
    UniProt
    O95342
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