ERCC2 antibody
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- Target See all ERCC2 Antibodies
- ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ERCC2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human ERCC2 (NP_001124339.1).
- Isotype
- IgG
- Top Product
- Discover our top product ERCC2 Primary Antibody
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- Application Notes
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
- Alternative Name
- ERCC2 (ERCC2 Products)
- Synonyms
- COFS2 antibody, EM9 antibody, TTD antibody, XPD antibody, AA407812 antibody, AU020867 antibody, AW240756 antibody, CXPD antibody, Ercc-2 antibody, MGC89573 antibody, CG9433 antibody, DhR3 antibody, DhXPD antibody, DmXPD antibody, Dmel\\CG9433 antibody, ERCC2 antibody, XPD/ERCC2 antibody, l(2)SH2 2137 antibody, l(2)SH2137 antibody, xpd antibody, zgc:56365 antibody, ERCC excision repair 2, TFIIH core complex helicase subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 2 antibody, excision repair cross-complementation group 2 antibody, Xeroderma pigmentosum D antibody, ERCC2 antibody, Ercc2 antibody, ercc2 antibody, Xpd antibody
- Background
- The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
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Observed_MW: 80 kDa
Calculated_MW: 46 kDa/86 kDa
- Gene ID
- 2068
- UniProt
- P18074
- Pathways
- DNA Damage Repair
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