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CAND1 antibody

CAND1 Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7257782
  • Target See all CAND1 Antibodies
    CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
    Reactivity
    • 20
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 15
    • 5
    Rabbit
    Clonality
    • 16
    • 4
    Polyclonal
    Conjugate
    • 17
    • 1
    • 1
    • 1
    This CAND1 antibody is un-conjugated
    Application
    • 14
    • 10
    • 5
    • 5
    • 4
    • 3
    • 1
    Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human CAND1 (NP_060918.2).
    Isotype
    IgG
    Top Product
    Discover our top product CAND1 Primary Antibody
  • Application Notes
    IHC 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
    Alternative Name
    CAND1 (CAND1 Products)
    Synonyms
    TIP120 antibody, TIP120A antibody, ATCAND1 antibody, CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1 antibody, ETA2 antibody, HEMIVENATA antibody, HVE antibody, T8K22.14 antibody, T8K22_14 antibody, cullin-associated and neddylation dissociated antibody, Tip120 antibody, Tip120A antibody, fb78a05 antibody, wu:fb78a05 antibody, zgc:55729 antibody, tip120 antibody, tip120a antibody, cand2 antibody, 2310038O07Rik antibody, 6330512O03Rik antibody, AI195005 antibody, AI846556 antibody, D10Ertd516e antibody, Tp120a antibody, mKIAA0829 antibody, cullin associated and neddylation dissociated 1 antibody, cullin-associated and neddylation dissociated antibody, cullin-associated and neddylation-dissociated 1 antibody, cullin-associated and neddylation-dissociated 1 L homeolog antibody, cullin-associated NEDD8-dissociated protein 1 antibody, cullin associated and neddylation disassociated 1 antibody, CAND1 antibody, Cand1 antibody, cand1 antibody, cand1.L antibody, LOC100159824 antibody, LOC100177977 antibody
    Background
    This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants.
    Gene ID
    55832
    UniProt
    Q86VP6
    Pathways
    Regulation of Actin Filament Polymerization
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