NUDT15 antibody
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- Target See all NUDT15 Antibodies
- NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NUDT15 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human NUDT15 (NP_060753.1).
- Isotype
- IgG
- Top Product
- Discover our top product NUDT15 Primary Antibody
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- Application Notes
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
- Alternative Name
- NUDT15 (NUDT15 Products)
- Synonyms
- MTH2 antibody, RP11-90M2.1 antibody, 6530403O17 antibody, A730068G11Rik antibody, nudix hydrolase 15 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 15 antibody, NUDT15 antibody, Nudt15 antibody
- Background
- This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.
- Molecular Weight
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Observed_MW: 19 kDa
Calculated_MW: 18 kDa
- Gene ID
- 55270
- UniProt
- Q9NV35
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