CD16 antibody, CD16b antibody, FCG3 antibody, FCGR3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody, FcRIII antibody, Fc fragment of IgG receptor IIIb antibody, Fc receptor, IgG, low affinity III antibody, Fc fragment of IgG receptor IIIa antibody, Fc-gamma RIII antibody, FCGR3B antibody, Fcgr3 antibody, FCGR3A antibody, FCGR3 antibody
Background
The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.