LIMS1 antibody

Catalog No. ABIN7257469

Product Details anti-LIMS1 Antibody

Target: LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIMS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human LIMS1 (NP_001180417.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LIMS1

Target: LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))

Alternative Name: LIMS1 (LIMS1 Products)

Synonyms: PINCH antibody, PINCH-1 antibody, PINCH1 antibody, Pinch1 antibody, RGD1560732 antibody, LIMS3 antibody, LIMS3L antibody, 2310016J22Rik antibody, 4921524A02Rik antibody, AI507642 antibody, AU021743 antibody, AW551584 antibody, C430041B13Rik antibody, Lims1l antibody, LIM zinc finger domain containing 1 antibody, LIM and senescent cell antigen-like domains 1 antibody, LIMS1 antibody, Lims1 antibody

Background: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 37 kDa

Calculated_MW: 37 kDa/38 kDa/41 kDa/44 kDa

Gene ID: 3987

UniProt: P48059