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TICAM1 antibody
TICAM1
Reactivity: Human, Mouse, Rat
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TICAM1 Antibody
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Target
See all TICAM1 Antibodies
TICAM1
(Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
Reactivity
All reactivities for TICAM1 antibodies
Human, Mouse, Rat
Host
All hosts for TICAM1 antibodies
Rabbit
Clonality
All clonalities for TICAM1 antibodies
Polyclonal
Conjugate
All conjugates for TICAM1 antibodies
This TICAM1 antibody is un-conjugated
Application
All applications for TICAM1 antibodies
Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human TICAM1 (NP_891549.1).
Isotype
IgG
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Discover our top product TICAM1 Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for TICAM1
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Target
TICAM1
(Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
Alternative Name
TICAM1 (TICAM1 Products )
Synonyms
IIAE6 antibody, MyD88-3 antibody, PRVTIRB antibody, TICAM-1 antibody, TRIF antibody, AW046014 antibody, AW547018 antibody, trif antibody, toll like receptor adaptor molecule 1 antibody, toll-like receptor adaptor molecule 1 antibody, TICAM1 antibody, Ticam1 antibody, ticam1 antibody
Background
This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.
Gene ID
148022
UniProt
Q8IUC6
Pathways
TLR Signaling , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Hepatitis C , Toll-Like Receptors Cascades
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