×
For best experience we recommend to activate Javascript in your browser.
EIF2AK2 antibody
EIF2AK2
Reactivity: Human, Rat
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-EIF2AK2 Antibody
(hide)
Target
See all EIF2AK2 Antibodies
EIF2AK2
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
Reactivity
All reactivities for EIF2AK2 antibodies
Human, Rat
Host
All hosts for EIF2AK2 antibodies
Rabbit
Clonality
All clonalities for EIF2AK2 antibodies
Polyclonal
Conjugate
All conjugates for EIF2AK2 antibodies
This EIF2AK2 antibody is un-conjugated
Application
All applications for EIF2AK2 antibodies
Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant protein of mouse Eif2ak2
Isotype
IgG
Top Product
Discover our top product EIF2AK2 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for EIF2AK2
(hide)
Target
EIF2AK2
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
Alternative Name
Eif2ak2 (EIF2AK2 Products )
Synonyms
PKR antibody, pkr antibody, EIF2AK2 antibody, DKFZp469K1934 antibody, EIF2AK1 antibody, PRKR antibody, 2310047A08Rik antibody, 4732414G15Rik antibody, AI467567 antibody, AI747578 antibody, Pkr antibody, Prkr antibody, Tik antibody, eukaryotic translation initiation factor 2 alpha kinase 2 antibody, eukaryotic translation initiation factor 2-alpha kinase 2 antibody, EIF2AK2 antibody, eif2ak2 antibody, Eif2ak2 antibody
Background
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
19106
UniProt
Q03963
Pathways
DNA Damage Repair , ER-Nucleus Signaling , Hepatitis C
Recently viewed
(hide)