GSTM2 antibody

Catalog No. ABIN7257070

Product Details anti-GSTM2 Antibody

Target: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human GSTM2 (NP_000839.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GSTM2

Target: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Alternative Name: GSTM2 (GSTM2 Products)

Synonyms: GSTA4 antibody, GST4 antibody, GSTM antibody, GSTM2-2 antibody, GTHMUS antibody, Gstb-2 antibody, Gstb2 antibody, GSTIV antibody, glutathione S-transferase mu 2 antibody, glutathione S-transferase mu 2 (muscle) antibody, glutathione S-transferase Mu 2 antibody, glutathione S-transferase, mu 2 antibody, glutathione S-transferase 2 antibody, Glutathione S-transferase 4 antibody, Gstm2 antibody, GSTM2 antibody, LOC100732167 antibody, gst2 antibody, gst-4 antibody

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Molecular Weight:

Observed_MW: 27 kDa

Calculated_MW: 22 kDa/25 kDa

Gene ID: 2946

UniProt: P28161

Pathways: Negative Regulation of Transporter Activity