UNC13D antibody
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- Target See all UNC13D Antibodies
- UNC13D (Unc-13 Homolog D (UNC13D))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UNC13D antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human UNC13D (NP_954712.1).
- Isotype
- IgG
- Top Product
- Discover our top product UNC13D Primary Antibody
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- Application Notes
- WB 1:1000-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- UNC13D (Unc-13 Homolog D (UNC13D))
- Alternative Name
- UNC13D (UNC13D Products)
- Synonyms
- FHL3 antibody, HLH3 antibody, HPLH3 antibody, Munc13-4 antibody, UNC13D antibody, 2610108D09Rik antibody, Jinx antibody, mFLJ00067 antibody, Unc13h4 antibody, BIGH3 antibody, CDB1 antibody, CDG2 antibody, CDGG1 antibody, CSD antibody, CSD1 antibody, CSD2 antibody, CSD3 antibody, EBMD antibody, LCD1 antibody, unc-13 homolog D antibody, unc-13 homolog D (C. elegans) antibody, transforming growth factor beta induced antibody, UNC13D antibody, Unc13d antibody, TGFBI antibody, unc13d antibody, un13d antibody
- Background
- This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
- Molecular Weight
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Observed_MW: 123 kDa
Calculated_MW: 41 kDa/123 kDa/128 kDa
- Gene ID
- 201294
- UniProt
- Q70J99
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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