DNAJB4 antibody

Catalog No. ABIN7256592

Product Details anti-DNAJB4 Antibody

Target: DNAJB4 (DnaJ (Hsp40) Homolog, Subfamily B, Member 4 (DNAJB4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJB4 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human DNAJB4 (NP_008965.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DNAJB4

Target: DNAJB4 (DnaJ (Hsp40) Homolog, Subfamily B, Member 4 (DNAJB4))

Alternative Name: DNAJB4 (DNAJB4 Products)

Synonyms: DNAJW antibody, DjB4 antibody, HLJ1 antibody, 1700029A20Rik antibody, 2010306G19Rik antibody, 5730460G06Rik antibody, zgc:91922 antibody, dnajb4 antibody, MGC83507 antibody, DNAJB4 antibody, DKFZp469B0618 antibody, DnaJ heat shock protein family (Hsp40) member B4 antibody, DnaJ (Hsp40) homolog, subfamily B, member 4 antibody, DnaJ heat shock protein family (Hsp40) member B4 S homeolog antibody, DnaJ homolog subfamily B member 4 antibody, putative dnaj homolog subfamily B member 4 antibody, DNAJB4 antibody, Dnajb4 antibody, dnajb4 antibody, dnajb4.S antibody, Bm1_16640 antibody, Smp_020920.1 antibody

Background: The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 38 kDa

Calculated_MW: 37 kDa

Gene ID: 11080

UniProt: Q9UDY4