Peroxiredoxin 3 antibody

Catalog No. ABIN7256588

Product Details anti-Peroxiredoxin 3 Antibody

Target: Peroxiredoxin 3 (PRDX3)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PRDX3 (NP_006784.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Peroxiredoxin 3

Target: Peroxiredoxin 3 (PRDX3)

Alternative Name: PRDX3 (PRDX3 Products)

Synonyms: cb718 antibody, wu:fk49e09 antibody, zgc:110282 antibody, zgc:112512 antibody, MGC83969 antibody, PRDX3 antibody, AOP-1 antibody, AOP1 antibody, HBC189 antibody, MER5 antibody, PRO1748 antibody, SP-22 antibody, prx-III antibody, AW822249 antibody, Aop1 antibody, D0Tohi1 antibody, Ef2l antibody, Mer5 antibody, Prx3 antibody, SP22 antibody, TDXM antibody, MTAP antibody, peroxiredoxin 3 antibody, peroxiredoxin 3 S homeolog antibody, peroxiredoxin PRX3 antibody, prdx3 antibody, PRDX3 antibody, prdx3.S antibody, PRX3 antibody, Prdx3 antibody

Background: This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.

Molecular Weight:

Observed_MW: 28 kDa

Calculated_MW: 25 kDa/27 kDa

Gene ID: 10935

UniProt: P30048

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process