×
For best experience we recommend to activate Javascript in your browser.
p300 antibody
EP300
Reactivity: Human, Mouse, Rat
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-p300 Antibody
(hide)
Target
See all p300 (EP300) Antibodies
p300 (EP300)
(E1A Binding Protein P300 (EP300))
Reactivity
All reactivities for p300 antibodies
Human, Mouse, Rat
Host
All hosts for p300 antibodies
Rabbit
Clonality
All clonalities for p300 antibodies
Polyclonal
Conjugate
All conjugates for p300 antibodies
This p300 antibody is un-conjugated
Application
All applications for p300 antibodies
Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human EP300 (NP_001420.2).
Isotype
IgG
Top Product
Discover our top product EP300 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for p300
(hide)
Target
p300 (EP300)
(E1A Binding Protein P300 (EP300))
Alternative Name
EP300 (EP300 Products )
Synonyms
KAT3B antibody, RSTS2 antibody, p300 antibody, A430090G16 antibody, A730011L11 antibody, p300 HAT antibody, E1A binding protein p300 antibody, histone acetyltransferase p300 antibody, EP300 antibody, LOC446056 antibody, ep300 antibody, Ep300 antibody
Background
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
Gene ID
2033
UniProt
Q09472
Pathways
p53 Signaling , Notch Signaling , Interferon-gamma Pathway , Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Intracellular Steroid Hormone Receptor Signaling , Regulation of Lipid Metabolism by PPARalpha , Regulation of Muscle Cell Differentiation , Regulation of Cell Size
Recently viewed
(hide)