Septin 5 antibody
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- Target See all Septin 5 (SEPT5) Antibodies
- Septin 5 (SEPT5)
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Septin 5 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human 44079 (NP_002679.2).
- Isotype
- IgG
- Top Product
- Discover our top product SEPT5 Primary Antibody
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- Application Notes
- IHC 1:100-1:200 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Septin 5 (SEPT5)
- Alternative Name
- SEPT5 (SEPT5 Products)
- Synonyms
- sept5 antibody, fj37h04 antibody, zgc:73218 antibody, wu:fj37h04 antibody, SEPT5 antibody, Cdcrel-1 antibody, Cdcrel1 antibody, Pnutl1 antibody, 5-Sep antibody, CDCrel-1A antibody, CDCREL antibody, CDCREL-1 antibody, CDCREL1 antibody, H5 antibody, HCDCREL-1 antibody, PNUTL1 antibody, septin 5a antibody, septin 5 antibody, sept5a antibody, SEPT5 antibody, sept5 antibody, Sept5 antibody
- Background
- This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.
- Gene ID
- 5413
- UniProt
- Q99719
- Pathways
- Synaptic Vesicle Exocytosis
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