RUFY3 antibody

Catalog No. ABIN7256440

Product Details anti-RUFY3 Antibody

Target: RUFY3 (RUN and FYVE Domain Containing 3 (RUFY3))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUFY3 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human RUFY3 (NP_055776.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RUFY3

Target: RUFY3 (RUN and FYVE Domain Containing 3 (RUFY3))

Alternative Name: RUFY3 (RUFY3 Products)

Background: This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 56 kDa

Calculated_MW: 52 kDa/55 kDa/64 kDa/70 kDa

Gene ID: 22902

UniProt: Q7L099