XRCC6BP1 antibody

Catalog No. ABIN7256430

Product Details anti-XRCC6BP1 Antibody

Target: XRCC6BP1 (XRCC6 Binding Protein 1 (XRCC6BP1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRCC6BP1 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human ATP23 (NP_150592.1).

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for XRCC6BP1

Target: XRCC6BP1 (XRCC6 Binding Protein 1 (XRCC6BP1))

Alternative Name: ATP23 (XRCC6BP1 Products)

Background: The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 28 kDa

Calculated_MW: 28 kDa

Gene ID: 91419

UniProt: Q9Y6H3