HLA-B antibody
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- Target See all HLA-B Antibodies
- HLA-B (Major Histocompatibility Complex, Class I, B (HLA-B))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HLA-B antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide of human HLA-B (NP_005505.2).
- Isotype
- IgG
- Top Product
- Discover our top product HLA-B Primary Antibody
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anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 75-107), (N-Term) antibody
HLA-B Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB47637 unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 26-309) antibodyHLA-B Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 241-362) antibodyHLA-B Reactivity: Human WB, ELISA, FACS, IHC Host: Mouse Monoclonal 2A11G7 unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 1-100) antibodyHLA-B Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 25-308) antibodyHLA-B Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 62-90), (N-Term) antibodyHLA-B Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB20998 unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 209-295) antibodyHLA-B Reactivity: Human ELISA Host: Mouse Monoclonal 4D4B6 unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 1-362) antibodyHLA-B Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 243-308) antibodyHLA-B Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 197-306) antibodyHLA-B Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:1000-1:2000 IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- HLA-B (Major Histocompatibility Complex, Class I, B (HLA-B))
- Alternative Name
- HLA-B (HLA-B Products)
- Background
- HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
- Molecular Weight
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Observed_MW: 40 kDa
Calculated_MW: 40 kDa
- Gene ID
- 3106
- UniProt
- P01889
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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