CDK11 antibody

Catalog No. ABIN7256386

Product Details anti-CDK11 Antibody

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK11 antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CDK11B (NP_277021.2).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDK11

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Alternative Name: CDK11B (CDK11B Products)

Synonyms: CDC2L1 antibody, CDK11 antibody, CDK11-p110 antibody, CDK11-p46 antibody, CDK11-p58 antibody, CLK-1 antibody, PK58 antibody, p58 antibody, p58CDC2L1 antibody, p58CLK-1 antibody, AA989746 antibody, Cdc11b antibody, Cdc2l1 antibody, Cdc2l2 antibody, Cdk11 antibody, CDC2L2 antibody, CDK11B antibody, cdc2l1 antibody, im:7142267 antibody, zgc:101589 antibody, cdc2l2 antibody, cdk11 antibody, cdk11-p110 antibody, cdk11-p46 antibody, cdk11-p58 antibody, cdk11b antibody, clk-1 antibody, p58cdc2l1 antibody, p58clk-1 antibody, pk58 antibody, cyclin dependent kinase 11B antibody, cyclin-dependent kinase 11B antibody, cyclin-dependent kinase 11B S homeolog antibody, CDK11B antibody, Cdk11b antibody, LOC489591 antibody, cdk11b antibody, cdk11b.S antibody

Background: This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.

Gene ID: 984

UniProt: P21127

Pathways: Regulation of Lipid Metabolism by PPARalpha, M Phase