STXBP2 antibody

Catalog No. ABIN7256166

Product Details anti-STXBP2 Antibody

Target: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXBP2 antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human STXBP2 (NP_001120868.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STXBP2

Target: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Alternative Name: STXBP2 (STXBP2 Products)

Synonyms: zgc:85807 antibody, FHL5 antibody, Hunc18b antibody, MUNC18-2 antibody, UNC18-2 antibody, UNC18B antibody, pp10122 antibody, C79054 antibody, Munc-18-2 antibody, Munc-18b antibody, Munc18b antibody, Sxtbp2 antibody, Sxtp2 antibody, Unc18-2 antibody, Unc18b antibody, muSec1 antibody, MUNC-18-2 antibody, syntaxin binding protein 2 antibody, stxbp2 antibody, STXBP2 antibody, Stxbp2 antibody

Background: This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene ID: 6813

UniProt: Q15833

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis