SARS2 antibody

Catalog No. ABIN7256012

Product Details anti-SARS2 Antibody

Target: SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARS2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SARS2 (NP_060297.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SARS2

Target: SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))

Alternative Name: SARS2 (SARS2 Products)

Synonyms: 2410015F05Rik antibody, D7Ertd353e antibody, SerRS antibody, SerRSmt antibody, SARS antibody, SARSM antibody, SERS antibody, SYS antibody, mtSerRS antibody, seryl-aminoacyl-tRNA synthetase 2 antibody, seryl-tRNA synthetase 2, mitochondrial antibody, Sars2 antibody, SARS2 antibody

Background: This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.

Gene ID: 54938

UniProt: Q9NP81