AKR7A2 antibody

Catalog No. ABIN7256002

Product Details anti-AKR7A2 Antibody

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR7A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human AKR7A2 (NP_003680.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AKR7A2

Target: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Alternative Name: AKR7A2 (AKR7A2 Products)

Synonyms: AFAR antibody, AFAR1 antibody, AFB1-AR1 antibody, AKR7 antibody, Aiar antibody, akr7a2 antibody, aldo-keto reductase family 7 member A2 antibody, aldo-keto reductase family 7, member A2 antibody, aldo-keto reductase family 7, member A2 L homeolog antibody, AKR7A2 antibody, Akr7a2 antibody, akr7a2.L antibody

Background: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 35 kDa

Calculated_MW: 39 kDa

Gene ID: 8574

UniProt: O43488