RRBP1 antibody

Catalog No. ABIN7255986

Product Details anti-RRBP1 Antibody

Target: RRBP1 (Ribosome Binding Protein 1 (RRBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRBP1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human RRBP1 (NP_004578.2).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RRBP1

Target: RRBP1 (Ribosome Binding Protein 1 (RRBP1))

Alternative Name: RRBP1 (RRBP1 Products)

Synonyms: 1700087N07Rik antibody, 5730465C04Rik antibody, ES/130 antibody, mKIAA1398 antibody, mRRp0 antibody, mRRp1.8 antibody, mRRp10 antibody, mRRp15a antibody, mRRp15b antibody, mRRp16.8 antibody, mRRp2 antibody, mRRp41 antibody, mRRp47 antibody, mRRp5.4 antibody, p180 antibody, ES130 antibody, RRp antibody, hES antibody, P180 antibody, rrbp1 antibody, sb:cb489 antibody, wu:fc47a01 antibody, ribosome binding protein 1 antibody, ribosome binding protein 1 homolog 180kDa (dog) antibody, ribosome binding protein 1b antibody, Rrbp1 antibody, RRBP1 antibody, rrbp1b antibody

Background: This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.

Gene ID: 6238

UniProt: Q9P2E9