DDX3Y antibody

Catalog No. ABIN7255736

Product Details anti-DDX3Y Antibody

Target: DDX3Y (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, Y-Linked (DDX3Y))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX3Y antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human DDX3Y (NP_001116137.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100 IF 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DDX3Y

Target: DDX3Y (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, Y-Linked (DDX3Y))

Alternative Name: DDX3Y (DDX3Y Products)

Synonyms: DBY antibody, DDX3Y antibody, 8030469F12Rik antibody, D1Pas1-rs1 antibody, Dby antibody, DEAD-box helicase 3, Y-linked antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked antibody, DDX3Y antibody, Ddx3y antibody

Background: The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene ID: 8653

UniProt: O15523