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NCOA1 antibody
NCOA1
Reactivity: Human, Mouse
IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NCOA1 Antibody
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Target
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NCOA1
(Nuclear Receptor Coactivator 1 (NCOA1))
Reactivity
All reactivities for NCOA1 antibodies
Human, Mouse
Host
All hosts for NCOA1 antibodies
Rabbit
Clonality
All clonalities for NCOA1 antibodies
Polyclonal
Conjugate
All conjugates for NCOA1 antibodies
This NCOA1 antibody is un-conjugated
Application
All applications for NCOA1 antibodies
Immunofluorescence (IF)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human NCOA1 (NP_003734.3).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
IF 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for NCOA1
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Target
NCOA1
(Nuclear Receptor Coactivator 1 (NCOA1))
Alternative Name
NCOA1 (NCOA1 Products )
Synonyms
F-SRC-1 antibody, KAT13A antibody, RIP160 antibody, SRC1 antibody, bHLHe42 antibody, bHLHe74 antibody, si:dkey-5g7.6 antibody, si:dkey-34f16.6 antibody, NCOA1 antibody, SRC-1 antibody, nuclear receptor coactivator 1 antibody, NCOA1 antibody, ncoa1 antibody, Ncoa1 antibody
Background
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
8648
UniProt
Q15788
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway , Nuclear Hormone Receptor Binding , Chromatin Binding , Regulation of Lipid Metabolism by PPARalpha
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