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YWHAE antibody

YWHAE Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7255377
  • Target See all YWHAE Antibodies
    YWHAE (14-3-3 epsilon (YWHAE))
    Reactivity
    • 57
    • 43
    • 39
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 54
    • 4
    • 1
    Rabbit
    Clonality
    • 48
    • 11
    Polyclonal
    Conjugate
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This YWHAE antibody is un-conjugated
    Application
    • 42
    • 16
    • 13
    • 13
    • 12
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human YWHAE (NP_006752.1).
    Isotype
    IgG
    Top Product
    Discover our top product YWHAE Primary Antibody
  • Application Notes
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    YWHAE (14-3-3 epsilon (YWHAE))
    Alternative Name
    YWHAE (YWHAE Products)
    Background
    This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
    Gene ID
    7531
    UniProt
    P62258
    Pathways
    Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
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