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TYMS antibody
TYMS
Reactivity: Human, Mouse, Rat
IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TYMS Antibody
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Target
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TYMS
(Thymidylate Synthetase (TYMS))
Reactivity
All reactivities for TYMS antibodies
Human, Mouse, Rat
Host
All hosts for TYMS antibodies
Rabbit
Clonality
All clonalities for TYMS antibodies
Polyclonal
Conjugate
All conjugates for TYMS antibodies
This TYMS antibody is un-conjugated
Application
All applications for TYMS antibodies
Immunofluorescence (IF)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human TYMS (NP_001062.1).
Isotype
IgG
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Discover our top product TYMS Primary Antibody
Alternatives
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Application Details
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Application Notes
IF 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for TYMS
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Target
TYMS
(Thymidylate Synthetase (TYMS))
Alternative Name
TYMS (TYMS Products )
Synonyms
FN1 antibody, ECK2823 antibody, JW2795 antibody, ts antibody, Ts antibody, HST422 antibody, TMS antibody, TS antibody, thymidylate synthetase antibody, contains intron in T4 phage antibody, ThyE antibody, thymidylate synthase antibody, thymidylate synthetase L homeolog antibody, TYMS antibody, thyA antibody, td antibody, thyE antibody, DDA3937_RS04960 antibody, tyms.L antibody, XBJ1_RS15770 antibody, EAMY_RS20680 antibody, Tyms antibody
Target Type
Viral Protein
Background
Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.
Gene ID
7298
UniProt
P04818
Pathways
Mitotic G1-G1/S Phases
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