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KIF14 antibody

KIF14 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7255237
  • Target See all KIF14 Antibodies
    KIF14 (Kinesin Family Member 14 (KIF14))
    Reactivity
    • 23
    • 3
    • 3
    • 1
    Human, Mouse, Rat
    Host
    • 22
    • 1
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIF14 antibody is un-conjugated
    Application
    • 12
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human KIF14 (NP_055690.1).
    Isotype
    IgG
  • Application Notes
    IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KIF14 (Kinesin Family Member 14 (KIF14))
    Alternative Name
    KIF14 (KIF14 Products)
    Synonyms
    wu:fi16h07 antibody, si:dkey-39e8.3 antibody, KIF14 antibody, D1Ertd367e antibody, E130203M01 antibody, kinesin family member 14 antibody, kinesin-like protein KIF14 antibody, KIF14 antibody, kif14 antibody, LOC100641544 antibody, Kif14 antibody
    Background
    This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants.
    Gene ID
    9928
    UniProt
    Q15058
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