beta Arrestin 1 antibody
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- Target See all beta Arrestin 1 (ARRB1) Antibodies
- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This beta Arrestin 1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human ARRB1 (NP_004032.2).
- Isotype
- IgG
- Top Product
- Discover our top product ARRB1 Primary Antibody
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anti-Arrestin, beta 1 (ARRB1) (AA 3-246) antibody
ARRB1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 169-418) antibodyARRB1 Reactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 336-363), (C-Term) antibodyARRB1 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB31615 unconjugated
anti-Arrestin, beta 1 (ARRB1) antibodyARRB1 Reactivity: Human, Mouse, Rat WB, IHC, IF, IP, FACS, ICC Host: Rabbit Monoclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 1-260) antibodyARRB1 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 369-418) antibodyARRB1 Reactivity: Human WB, IHC, ELISA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (AA 343-371), (C-Term) antibodyARRB1 Reactivity: Human WB, IF, IHC (p), FACS, EIA Host: Rabbit Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (Ser157) antibodyARRB1 Reactivity: Human, Monkey WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) (C-Term) antibodyARRB1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Arrestin, beta 1 (ARRB1) antibodyARRB1 Reactivity: Human, Mouse, Rat IHC, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC 1:50-1:200 IF 1:20-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
- Alternative Name
- ARRB1 (ARRB1 Products)
- Background
- Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.
- Gene ID
- 408
- UniProt
- P49407
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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