CDK9 antibody

Catalog No. ABIN7255025

Product Details anti-CDK9 Antibody

Target: CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK9 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CDK9 (NP_001252.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDK9

Target: CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

Alternative Name: CDK9 (CDK9 Products)

Synonyms: C-2k antibody, CDC2L4 antibody, CTK1 antibody, PITALRE antibody, TAK antibody, wu:fb22e09 antibody, wu:fc06c02 antibody, c-2k antibody, cdc2l4 antibody, cdk9 antibody, ctk1 antibody, pitalre antibody, tak antibody, CDK9 antibody, CG5179 antibody, Dmel\\CG5179 antibody, P-TEF antibody, P-TEFb antibody, PTefb antibody, cyclin dependent kinase 9 antibody, cyclin-dependent kinase 9 (CDC2-related kinase) antibody, cyclin-dependent kinase 9 L homeolog antibody, cyclin-dependent kinase 9 antibody, Cyclin-dependent kinase 9 antibody, cyclin-dependent kinase 9 S homeolog antibody, CDK9 antibody, cdk9 antibody, cdk9.L antibody, Cdk9 antibody, cdk9.S antibody

Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

Gene ID: 1025

UniProt: P50750

Pathways: Cell Division Cycle