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NEDD4 antibody
NEDD4
Reactivity: Human
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NEDD4 Antibody
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Target
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NEDD4
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4))
Reactivity
All reactivities for NEDD4 antibodies
Human
Host
All hosts for NEDD4 antibodies
Rabbit
Clonality
All clonalities for NEDD4 antibodies
Polyclonal
Conjugate
All conjugates for NEDD4 antibodies
This NEDD4 antibody is un-conjugated
Application
All applications for NEDD4 antibodies
Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human NEDD4 (NP_940682.2).
Isotype
IgG
Top Product
Discover our top product NEDD4 Primary Antibody
Alternatives
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anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4) (AA 801-900) antibody
NEDD4
Reactivity: Human, Rat
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for NEDD4
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Target
NEDD4
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase (NEDD4))
Alternative Name
NEDD4 (NEDD4 Products )
Synonyms
NEDD4-1 antibody, RPF1 antibody, AA959633 antibody, AL023035 antibody, AU019897 antibody, E430025J12Rik antibody, Nedd4-1 antibody, Nedd4a antibody, mKIAA0093 antibody, CG32184 antibody, CG42279 antibody, CG7555 antibody, DNedd4 antibody, Dmel\\CG42279 antibody, Dmel_CG32184 antibody, Dmel_CG7555 antibody, dNedd4 antibody, dNedd4-1 antibody, nedd4 antibody, GB16853 antibody, NEDD4 antibody, Nedd4 antibody, neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase antibody, neural precursor cell expressed, developmentally down-regulated 4 antibody, CG42279 gene product from transcript CG42279-RJ antibody, E3 ubiquitin-protein ligase Nedd-4 antibody, E3 ubiquitin-protein ligase NEDD4 antibody, NEDD4 antibody, Nedd4 antibody, LOC411723 antibody, LOC100457150 antibody, nedd4 antibody, LOC100547485 antibody
Background
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
Gene ID
4734
UniProt
P46934
Pathways
Notch Signaling , Intracellular Steroid Hormone Receptor Signaling Pathway , Skeletal Muscle Fiber Development , Signaling Events mediated by VEGFR1 and VEGFR2
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