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NEFL antibody
NEFL
Reactivity: Human, Rat, Mouse
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NEFL Antibody
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Target
See all NEFL Antibodies
NEFL
(Neurofilament, Light Polypeptide (NEFL))
Reactivity
All reactivities for NEFL antibodies
Human, Rat, Mouse
Host
All hosts for NEFL antibodies
Rabbit
Clonality
All clonalities for NEFL antibodies
Polyclonal
Conjugate
All conjugates for NEFL antibodies
This NEFL antibody is un-conjugated
Application
All applications for NEFL antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human NEFL (NP_006149.2).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200 IF 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for NEFL
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Target
NEFL
(Neurofilament, Light Polypeptide (NEFL))
Alternative Name
NEFL (NEFL Products )
Synonyms
NEFL antibody, nefl antibody, zgc:136626 antibody, AI847934 antibody, CMT2E antibody, NF-L antibody, NF68 antibody, Nfl antibody, CMT1F antibody, NFL antibody, XNF-L antibody, neurofilament light antibody, neurofilament, light polypeptide antibody, neurofilament, light polypeptide b antibody, neurofilament, light L homeolog antibody, NEFL antibody, neflb antibody, Nefl antibody, nefl.L antibody
Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Gene ID
4747
UniProt
P07196
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