ARHGDIB antibody

Catalog No. ABIN7254544

Product Details anti-ARHGDIB Antibody

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGDIB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human ARHGDIB

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARHGDIB

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Alternative Name: ARHGDIB (ARHGDIB Products)

Synonyms: ARHGDIB antibody, zgc:65966 antibody, arhgdib antibody, MGC69067 antibody, gdia2 antibody, rhodgi-2 antibody, rhodgi2 antibody, D4 antibody, GDIA2 antibody, GDID4 antibody, LYGDI antibody, Ly-GDI antibody, RAP1GN1 antibody, RhoGDI2 antibody, Gdid4 antibody, Rho GDP dissociation inhibitor (GDI) gamma antibody, Rho GDP dissociation inhibitor (GDI) beta S homeolog antibody, Rho GDP dissociation inhibitor beta antibody, Rho GDP dissociation inhibitor (GDI) beta antibody, Rho, GDP dissociation inhibitor (GDI) beta antibody, arhgdig antibody, arhgdib.S antibody, ARHGDIB antibody, arhgdib antibody, Arhgdib antibody

Background: ARHGDIB,also known as RhoGDI2,is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them,and the subsequent binding of GTP to them. It is mainly in hematopoietic,endothelial,and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types,such as bladder,lung and lymphoma,but is upregulated in prostate and gastric cancer.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 23 kDa

UniProt: P52566

Pathways: Caspase Cascade in Apoptosis