BRI3BP antibody

Catalog No. ABIN7254535

Product Details anti-BRI3BP Antibody

Target: BRI3BP (BRI3 Binding Protein (BRI3BP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRI3BP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human BRI3BP

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BRI3BP

Target: BRI3BP (BRI3 Binding Protein (BRI3BP))

Alternative Name: BRI3BP (BRI3BP Products)

Synonyms: fa20c12 antibody, wu:fa20c12 antibody, kg19 antibody, bnas1 antibody, hccr-2 antibody, BNAS1 antibody, HCCR-1 antibody, HCCR-2 antibody, HCCRBP-1 antibody, KG19 antibody, 2410150I18Rik antibody, AI841257 antibody, AW742481 antibody, bri3 binding protein antibody, BRI3 binding protein pseudogene antibody, BRI3 binding protein L homeolog antibody, BRI3 binding protein antibody, Bri3 binding protein antibody, bri3bp antibody, LOC452360 antibody, bri3bp.L antibody, BRI3BP antibody, Bri3bp antibody

Background: BRI3BP (BRI3 binding protein), also known as BNAS1, HCCR-1, I3-binding protein or cervical cancer 1 proto-oncogene-binding protein KG19, is a 251 amino acid multi-pass membrane protein. Though widely expressed, BRI3BP is found at highest levels in brain, kidney and liver where it localizes to the endoplasmic reticulum (ER) and is involved in ER structural dynamics and mitochondrial viability. Possessing pro-apoptotic properties and the ability to potentiate drug-induced apoptosis, BRI3BP overexpression has been shown to enhance caspase-3 and mitochondrial cytochrome c release in etoposide-treated human embryonic kidney 293T cells.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 28 kDa

UniProt: Q8WY22