KRTAP11-1 antibody

Catalog No. ABIN7006990

Product Details anti-KRTAP11-1 Antibody

Target: KRTAP11-1 (Keratin Associated Protein 11-1 (KRTAP11-1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRTAP11-1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human KRTAP11-1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KRTAP11-1

Target: KRTAP11-1 (Keratin Associated Protein 11-1 (KRTAP11-1))

Alternative Name: KRTAP11-1 (KRTAP11-1 Products)

Synonyms: HACL1 antibody, HACL-1 antibody, KAP11.1 antibody, Hacl1 antibody, PRED29 antibody, AA162070 antibody, AA589467 antibody, AV018433 antibody, keratin associated protein 11-1 antibody, keratin-associated protein 11-1 antibody, KRTAP11-1 antibody, Krtap11-1 antibody, LOC694859 antibody

Background: Hair is a structure that is unique to mammals. It plays an important role in the retention of heat, as well as sexual dimorphism, attraction of mates and protection of skin. The major components of hair are -keratins and keratin-associated proteins (KRTAPs or KAPs), each of which are encoded by multigene families. Hair keratins form an intermediate filament (IF) network, which is embedded in an interfilamentous matrix consisting of KRTAPs. KRTAPS comprise three major groups, which are essential for the formation of rigid and resistant hair shafts through disulfide bond cross-linking or hydrophobic interactions with keratins. These groups are designated high cysteine (HS), which includes subfamilies 1, 2, 3, 10, 12, 16, 29 and 31, ultrahigh cysteine, including subfamilies 4, 5, 9, 17, 28, 30, 32 and 33, and high glycine-tyrosine (HGT), which includes subfamilies 6, 7, 8, 19, 20 and 21. In addition, subfamilies 11, 13, 24-27, 29, 34 and 35 have high serine content but relative low cysteine content. After further phylogenetic studies, subfamilies 14 and 15 have been grouped with subfamily 13 and subfamily 22 was combined with subfamily 19.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 17 kDa

UniProt: Q8IUC1