PSCA antibody

Catalog No. ABIN7254328

Product Details anti-PSCA Antibody

Target: PSCA (Prostate Stem Cell Antigen (PSCA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSCA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human PSCA

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.78 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PSCA

Target: PSCA (Prostate Stem Cell Antigen (PSCA))

Alternative Name: PSCA (PSCA Products)

Background: PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40 % of primary prostate cancers and in as many as 100 % of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 13 kDa

UniProt: O43653